Ebola
virus disease (EVD)
or Ebola hemorrhagic fever (EHF) is a disease of humans and other
primates caused by an ebolavirus. Symptoms start two days to three weeks after
contracting the virus, with a fever, sore throat, muscle pain and headaches. Typically, nausea,
vomiting and diarrhea follow, along with decreased functioning of the liver
and kidneys. Around this time, affected people may begin to bleed both within the body and externally.
The virus may be acquired upon contact with blood
or bodily fluids of an infected animal (commonly monkeys or fruit bats). Spreading through the air has not been documented
in the natural environment. Fruit bats are believed to carry and spread the
virus without being affected. Once human infection occurs, the disease may
spread between people, as well. Male survivors may be able to transmit the
disease via semen for nearly two months. To make the diagnosis, typically
other diseases with similar symptoms such as malaria, cholera and other viral hemorrhagic fevers
are first excluded. To confirm the diagnosis, blood samples are tested for
viral antibodies, viral RNA, or the virus itself
No specific treatment for the disease is yet available. Efforts to help those who are infected are supportive and include giving either oral rehydration therapy (slightly sweet and salty water to drink) or
intravenous fluids. The disease has a
high mortality
rate, often killing between 50% and 90% of those infected with the
virus. EVD was first
identified in Sudan and the Democratic Republic of the Congo. The disease typically
occurs in outbreaks in tropical regions of sub-Saharan
Africa. From 1976 (when
it was first identified) through 2013, fewer than 1,000 people per year have
been infected. The largest
outbreak to date is the ongoing 2014 West Africa Ebola outbreak, which is affecting Guinea, Sierra Leone, Liberia and Nigeria. As of August
2014, more than 1,750 suspected cases have been reported. Efforts are going
on to develop a vaccine; however, none yet
exists.
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